Table 8. 32 Factorial design results of DSC and FDM.
| Solution | % Mannitol* | % PVP K30* | Metastable form (Absence/Presence) | Tg’°C (DSC) | TCO°C (FDM) | Second lyophilisation viability test (Yes/No) |
|---|---|---|---|---|---|---|
| A | 2.0 | 3.0 | Absence | -29.1 | -29.0 | Yes |
| B | 4.5 | 3.0 | Presence | -36.0 | -34.0 | No |
| C | 7.0 | 3.0 | Presence | -30.4 | -29.0 | No |
| D | 2.0 | 5.0 | Absence | -27.3 | -31.0 | Yes |
| E | 4.5 | 5.0 | Absence | -32.2 | -31.0 | Yes |
| F | 7.0 | 5.0 | Presence | -33.2 | -39.0 | No |
| G | 2.0 | 1.0 | Presence | -34.0 | -36.0 | No |
| H | 4.5 | 1.0 | Presence | - 29.9 | -25.0 | No |
| I | 7.0 | 1.0 | Presence | -29.5 | -35.0 | No |
*(W/v).