Table 1.
Comparative summary of the two EU-funded sister projects arising from the PanCare Network.
| PanCareSurFup: PanCare childhood and adolescent cancer survivor care and follow-up studies | PanCareLIFE: PanCare studies in fertility and ototoxicity to improve quality of life after cancer during childhood, adolescence and young adulthood | |
|---|---|---|
| Main focus | Cardiotoxicity, second primary neoplasms, late mortality, guidelines for long-term follow-up and transition and models of care | Fertility, ototoxicity, health-related quality of life – combined with genetics |
| Participants (countries) | 16 Partners from 11 countries (Austria, Belgium, France, Germany, Hungary, Ireland, Italy, Netherlands, Sweden, Switzerland, UK) | 15 Partners from eight countries (Czech Republic, Denmark, France, Germany, Ireland, Italy, Netherlands, Switzerland) |
| Work packages | 1: Data collection and harmonisation (D. Grabow, Mainz, Germany) | 1: Data centre and biostatistical support (P. Kaatsch, Mainz, Germany) |
| 2: Radiation dosimetry (F. de Vathaire, Paris, France) | 2: Fertility preservation guidelines (L. Kremer, Amsterdam, Netherlands) | |
| 3: Cardiac disease: cohort and nested case-control study (L. Kremer, Amsterdam, Netherlands) | 3: Female fertility impairment (E. van Dulmen-den Broeder, Amsterdam, Netherlands) | |
| 4: Subsequent primary neoplasms: cohort and nested case-control studies (M. Hawkins, Birmingham, UK) | 4. Genetics of fertility impairment & hearing loss (M. van den Heuvel-Eibrink, Utrecht, Netherlands) | |
| 5: Late mortality (S. Garwicz, Lund, Sweden) | 5: Ototoxicity (T. Langer, Lübeck, Germany) | |
| 6: Guidelines, long-term follow-up and transition (R. Skinner, Newcastle, UK) | 6: Health-related quality of life (G. Calaminus, Münster, Germany) | |
| 7: Dissemination and Training (M. Jankovic, Monza, Italy) | 7: Dissemination and exploitation (C. Clissmann, Dublin, Ireland) | |
| 8: Management and coordination (L. Hjorth, Lund, Sweden) | 8: Project management (P. Kaatsch, Mainz, Germany) | |
| Start of 5-year project | February 2011 | November 2013 |
| Coordinator | L. Hjorth (Lund, Sweden) | P. Kaatsch (Mainz, Germany), Coordinator; J. Byrne (Drogheda, Ireland), Research Manager; C. Clissmann (Dublin, Ireland), Administrative Manager |
| Project Manager | E. Witthoff/H. Linge (Lund, Sweden) | D. Grabow (Mainz, Germany), H. Campbell (Drogheda, Ireland), K. O’Brien (Dublin, Ireland) |
| Ethical (both projects) and scientific (PCSF only) advisory board | J.D. Beck (Erlangen, Germany), G. Bode (Bonn, Germany), P. Inskip (Washington, US), M. Jenney (Cardiff, UK) | L.E. Knudsen, (Copenhagen, Denmark), N.W. Paul, (Mainz, Germany) |
| Grant | FP7-HEALTH-2010.2.4.1-7 (Grant Agreement Number 257505) | FP7-HEALTH-2013-INNOVATION-1 (Grant Agreement Number 602030) |