Fig. 2. Serum angiopoietin-like protein 4 and its mRNA expression in subcutaneous adipose tissue at baseline and after interventions.

Changes of ANGPTL4 levels after very-low-calorie diet (a), bariatric surgery (b), partial realimentation (c), acute fasting (d), parenteral nutrition (e), and changes of ANGPTL4 mRNA expression in SAT after very-low-calorie diet (f) and bariatric surgery (g). OB non-diabetic obese patients, T2DM obese patients with T2DM, AN patients with anorexia nervosa, SBS patients with short bowel syndrome. Values are mean ± SEM. *p < 0.05 vs. control subjects, one-way ANOVA/ANOVA on ranks; p < 0.05 vs. before VLCD/realimentation, paired t-test or Wilcoxon signed-rank test; ^xp < 0.05 vs. subjects with simple obesity, unpaired t-test or Mann–Whitney rank sum test; ¹p < 0.05 vs. V1, one-way RM ANOVA/one-way RM ANOVA on ranks, ²p < 0.05 vs. V2, one-way RM ANOVA/one-way RM ANOVA on ranks