. 2018 Apr 25;8:21. doi: 10.1038/s41387-018-0032-2

Table 2.

Anthropometric, biochemical, and hormonal characteristics of patients with obesity and type 2 diabetes mellitus undergoing bariatric surgery

	Controls	V1	V2	V3	V4
Number	22	13	13	13	13
Age (year)	51.6 ± 1.33	56.2 ± 2.13	NP	NP	NP
Body mass index (kg/m²)	23.4 ± 0.44	41.6 ± 1.69*	37.0 ± 1.63*	34.4 ± 1.79^,*	35.4 ± 1.79^,*
Blood glucose (mmol/l)	4.91 ± 0.08	10.2 ± 1.19*	6.47 ± 0.53^,*	6.69 ± 0.54^,*	8.12 ± 1.11*
HbA_1c (mmol/mol)	37.5 ± 0.81	66.3 ± 4.84*	54.6 ± 3.15^,*	53.4 ± 4.67^,*	53.9 ± 4.62^,*
Total cholesterol (mmol/l)	5.18 ± 0.22	5.35 ± 0.29	4.69 ± 0.35	4.96 ± 0.33	4.56 ± 0.16
Triglycerides (mmol/l)	1.12 ± 0.12	2.86 ± 0.73*	1.76 ± 0.24^,*	1.85 ± 0.28**	1.71 ± 0.26**
HDL cholesterol (mmol/l)	1.65 ± 0.07	1.21 ± 0.07*	1.09 ± 0.06*	1.26 ± 0.07^,**	1.29 ± 0.07^,**
LDL cholesterol (mmol/l)	3.03 ± 0.17	3.19 ± 0.33	2.81 ± 0.29	2.86 ± 0.26	2.50 ± 0.17
Insulin (mUI/l)	16.6 ± 0.76	97.1 ± 33.01*	65.7 ± 28.0*	72.5 ± 32.6^,*	64.0 ± 24.6*
Leptin (ng/ml)	13.3 ± 2.00	39.2 ± 5.82*	20.6 ± 4.10**	21.3 ± 5.18**	24.0 ± 5.71**
hsC-reactive protein (mg/l)	0.20 ± 0.05	3.88 ± 0.83*	2.04 ± 0.51*	2.50 ± 0.88*	1.61 ± 0.42^,*
HOMA index	3.64 ± 0.20	46.36 ± 19.67*	19.95 ± 8.93^,*	27.33 ± 14.26^,*	22.73 ± 9.36*
ANGPTL4 mRNA expression in SAT	1.04 ± 0.09	1.15 ± 0.17	1.25 ± 0.19	0.94 ± 0.15	1.10 ± 0.11

Values are mean ± SEM

NP non-measured parameter, V1 before bariatric surgery, V2 1 month after bariatric surgery, V3 3 months after bariatric surgery, V4 1 year after bariatric surgery

*p < 0.05 vs. controls, one-way ANOVA/ANOVA on ranks; **p < 0.05 vs. V1, one-way repeated measures ANOVA/one-way repeated measures ANOVA on ranks; ***p < 0.05 vs. V2, one-way repeated measures ANOVA/one-way repeated measures ANOVA on ranks