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. 2018 Apr 25;8:6546. doi: 10.1038/s41598-018-24973-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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HE staining of iTDM specimen harvested from the greater omentum after demineralization, embedding and section. In CLC groups (A: non-induced CLC; C: IF_CM–induced CLC; E: MF_CM-induced CLC) no evident attachment to the surface of iTDMs was formed, while periodontal ligament-like fibers were found to attach to the surface of iTDM with an angle in HERS groups. (B) Non-induced HERS cells formed the least amount of fibrous attachment to iTDM, IF_CM-induced HERS cells (D) formed more, and MF_CM-induced group (F) formed the most. The right column was the magnification of the black box in the left column, respectively. Scale bars: 100 μm.