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. 2018 Apr 25;8:6542. doi: 10.1038/s41598-018-24785-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Maximum-intensity-projection PET/CT images of ⁶⁴Cu-NODAGA-ZHER2:S1, ⁶⁴Cu-CB-TE2A-G-ZHER2:342 and ⁶⁴Cu-CB-TE2A-GEEE-ZHER2:342 at 2, 6, and 24 h after injection in mice bearing HER2-positive SKOV-3 xenografts. Arrows point at tumors. The scale was adjusted to provide clear visualization of hepatic uptake of ⁶⁴Cu-CB-TE2A-G-ZHER2:342342 and ⁶⁴Cu-NODAGA-ZHER2:S1. This resulted in saturation of tumor images (white spots).