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. 2018 Apr 19;5:72. doi: 10.3389/fmed.2018.00072

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Copyright © 2018 Sigdel, Mercer, Nandoe, Nicora, Burnum-Johnson, Qian and Sarwal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Boxplots of the number of unique viruses discovered by disease status. The boxplots show that the relative abundance of unique viruses discovered in stable and acute rejection (AR) patients is lower than the number discovered in healthy control (HC). The number of viruses discovered increased in chronic allograft nephropathy (CAN) above stable and AR. The number of viruses increased in BK over all immunosuppressed categories. T-Tests with Bonferroni corrections were used for multiple testing. *Significant at p < 0.05; **significant at p < 0.005; ***significant at p < 0.001.