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. 2018 Apr 19;9:791. doi: 10.3389/fimmu.2018.00791

Figure 1.

Figure 1

Complement activation of human plasma induced by the nanostructures. Different concentrations of the prototypes were tested by Western blot: 10, 100, and 1,000 µg/mL. Phosphate-buffered saline and cobra venom factor (CVF) were selected as negative and positive controls. Abbreviations: NE, nanoemulsion; CS NC, chitosan nanocapsule; PARG NC, polyarginine nanocapsule; PR NC: protamine nanocapsule. Bands corresponding to the C3 protein and C3 split products are indicated. Molecular weight controls are expressed in kilodalton. The lower graph corresponds to the intensity of the lower band (C3 cleaved) normalized to the negative control. The median ± SD is represented (n = 3). *Significant differences between negative and positive (CVF) controls or nanocapsule treatments.