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Kinetic internalization study of the labeled nanostructures performed on a confocal microscope [red channel: rhodamine 6G (labeled nanocapsules); blue channel: DAPI (nucleus)]. Raw 264.7 cells were incubated in the presence of the nanosystems, and images were acquired every 5 min. Images at 15, 30, 60, and 90 min are shown. Abbreviations: NE, nanoemulsion nanocapsule; CS NC, chitosan nanocapsule; PR NC, protamine nanocapsule; PARG NC, polyarginine nanocapsule.
