Table 2.
Untransformed values of neurodevelopmental parameters of tree shrew, macaque, rat/mouse and ferret used for statistical analysis.
Neurodevelopmental parameter | Rat/Mouse | Ferret | Tree shrew | Macaque | |
---|---|---|---|---|---|
1 | SVZ thickness at DL neurogenesis (μm) | 27 | 97 | 82.1 | 440 |
2 | SVZ thickness at UL neurogenesis (μm) | 237 | 545 | 467.034 | 2590 |
3 | Ratio of SVZ/VZ thickness at DL neurogenesis | 0.333 | 0.8 | 0.778 | 0.667 |
4 | Ratio of SVZ/VZ thickness at UL neurogenesis | 0.875 | 2.333 | 5.901 | 37.5 |
5 | Ratio of oSVZ/iSVZ thickness at UL neurogenesis | 0.975 | 1.148 | 6.436 | 4.18 |
6 | Ratio of Tbr2+ NPCs in SVZ/VZ at DL neurogenesis | 1.563 | 2.464 | 1.772 | 28.667 |
7 | Ratio of Tbr2+ NPCs in SVZ/VZ at UL neurogenesis | 1.196 | 4.581 | 16.813 | 39.4 |
8 | Ratio of Tbr2+ NPCs in oSVZ/iSVZ at UL neurogenesis | 0.134 | 0.331 | 2.337 | 1.736 |
9 | Ratio of Pax6+ NPCs in SVZ/VZ at DL neurogenesis | 0.104 | 0.056 | 0.219 | 0.125 |
10 | Ratio of Pax6+ NPCs in SVZ/VZ at UL neurogenesis | 0.138 | 0.697 | 4.131 | 3.85 |
11 | Ratio of Pax6+ NPCs in oSVZ/iSVZ at UL neurogenesis | 0.026 | 0.817 | 2.955 | 1.982 |
12 | Ratio of mitoses in SVZ/VZ | 0.678 | 1.529 | 2.276 | 1.788 |
13 | Relative abundance of bRG at UL neurogenesis (%) | 8.89 | 42 | 24.664 | 62 |
14 | Relative abundance of Pax6+ bRG at UL neurogenesis (%) | 100 | 100 | 86 | 91 |
15 | Relative abundance of Tbr2+ bRG at UL neurogenesis (%) | 75 | 0 | 23 | 44 |
Neurodevelopmental parameters of tree shrew were analyzed in this study. All other parameters were obtained from the literature (Table 1). VZ, ventricular zone; SVZ, subventricular zone; iSVZ, inner SVZ; oSVZ, outer SVZ; DL, deep-layer; UL, upper-layer. For details, see section “Materials and Methods.”