Table 6.
Pharmacokinetics properties of 2,6-octadienal, 3,7-dimethyl and 2-methyl-2-pentene
Name of
ligand |
GI absorption | BBB permeability | P-gp substrate | CYP 1A2 Inhibitor | CYP2C19 Inhibitor | CYP2C9 Inhibitor | CYP2D6 Inhibitor | CYP3A4 Inhibitor | Log K p (skin permeation) cm/s |
---|---|---|---|---|---|---|---|---|---|
2,6-Octadienal, 3,7-dimethyl | High | Yes | No | No | No | No | No | No | -5.08 |
2-Methyl-2-pentene | Low | Yes | No | No | No | No | No | No | -4.88 |
GI absorption: Gastrointestinal absorption, BBB: blood brain barrier, CYP: cytochrome P