Table 3.

Ceritinib dose modification patterns.

	Ceritinib patients (N = 164)
Starting dose, mean ± SD [median] – min – max (mg/day)	717.1 ± 95.5 [750] – 300 – 750
Dose, mean ± SD [median] – min – max (mg/day)	695.3 ± 107.1 [750] – 300 – 750
Dose modification patterns (mg/day), N (%)
750	121 (73.8%)
750 → 600	10 (6.1%)
600	9 (5.5%)
750 → 450	8 (4.9%)
450	6 (3.7%)
750 → 600 → 750	3 (1.8%)
300	3 (1.8%)
750 → 600 → 450	1 (0.6%)
300 → 450 → 600	1 (0.6%)
450 → 750 → 450 → 750	1 (0.6%)
600 → 450	1 (0.6%)

SD: standard deviation