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. 2018 Mar 12;7(1):21–27. doi: 10.1080/21556660.2018.1445092

Table 3.

Ceritinib dose modification patterns.

  Ceritinib patients (N = 164)
Starting dose, mean ± SD [median] – min – max (mg/day) 717.1 ± 95.5 [750] – 300 – 750
Dose, mean ± SD [median] – min – max (mg/day) 695.3 ± 107.1 [750] – 300 – 750
Dose modification patterns (mg/day), N (%)
750 121 (73.8%)
 750 → 600 10 (6.1%)
 600 9 (5.5%)
 750 → 450 8 (4.9%)
 450 6 (3.7%)
 750 → 600 → 750 3 (1.8%)
 300 3 (1.8%)
 750 → 600 → 450 1 (0.6%)
 300 → 450 → 600 1 (0.6%)
 450 → 750 → 450 → 750 1 (0.6%)
 600 → 450 1 (0.6%)

SD: standard deviation