Figure 1.

The effect of age on the absolute numbers of CD161-expressing T cells. (A) The absolute numbers of CD3⁺ T cells, as well as (B) CD4⁺ T cells and CD8⁺ T cells in the peripheral blood of 96 healthy subjects (age range 20–84). (C) Flow cytometric gating of CD161⁺ CD4⁺ T cells, CD161^high CD8⁺ T cells, and CD161^int CD8⁺ T cells in the peripheral blood of healthy young, intermediate, and old subjects. (D) The absolute numbers of CD161⁺ CD4⁺ T cells, CD161⁻ CD4⁺ T cells, and (E) CD161^high CD8⁺ T cells, CD161^int CD8⁺ T cells, and CD161⁻ CD8⁺ T cells in the peripheral blood of same donors as mentioned at (A,B). Statistical significance by Spearman’s rank test is shown.