Skip to main content
. 2018 Mar 19;141(5):1320–1333. doi: 10.1093/brain/awy062

Figure 6.

Figure 6

HnRNP A1B expression causes cell death. (A) Whole lysates of CB3 cells, which lack endogenous hnRNP A1 or were modified to re-express one of the isoforms, were immunoblotted for hnRNP A1/A1B (9H10) and actin. (B) Viability of CB3 cell lines was assayed by trypan blue dye exclusion. The mean ± SEM of three independent experiments is plotted. *P < 0.05 **P < 0.002. (C) Aggregation was assayed by filter retardation using non-binding cellulose acetate membranes and immunoblotted for hnRNP A1/A1B (9H10). Data are representative of three independent experiments.