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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Stem Cells. 2018 Jan 22;36(5):751–760. doi: 10.1002/stem.2771

Figure 2. Learning memory deficits in AKAP12 knockout mouse.

Figure 2

Wild-type (WT) and AKAP12 knockout (KO) mice were subjected to the standard Y-maze test to assess their working memory. (a) Schematics for Y-maze test. Please see the method section as to how to calculate alteration ratio in Y-maze test. (b) There were no differences in the total number of arm entry between WT and KO mice, suggesting that the locomotor activity of AKAP12 KO mice was similar to WT mice. Values are mean ± SD. N=17 for each group. (c) On the other hand, the alternation ratio (index of working memory) in AKAP12 KO mice was significantly lower compared to WT mice. Values are mean ± SD. N=17 for each group. *P<0.05. Please see Supplementary Figure S3 for our repeated experiments with different animals by another operator.