Mitochondrial Morphology in iPSCs and iPSC-CMs
(A) Transmission electron microscopy (TEM) was used to investigate the mitochondrial morphology changes during reprogramming and differentiation. The arrows show mitochondria.
(B) Morphometric analysis of mitochondrial length in HCM-iPSCs (n = 55), Con-iPSCs (n = 50), HCM-iPSC-CMs (n = 40), and Con-iPSC-CMs (n = 40).
(C) Relative mitochondrial content in HCM-iPSC-CMs (n = 40) compared with Con-iPSC-CMs (n = 40).
Data are represented as mean ± SEM. ∗p < 0.05, ∗∗∗p < 0.001.