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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Stem Cells. 2017 Jul 31;35(10):2138–2149. doi: 10.1002/stem.2669

Figure 4. microRNA profiling of exosomes harvested from ESC-CMs and iPSC-CMs under normoxic and hypoxic conditions.

Figure 4

(A–B) Characterization of exosomes by immunoblotting of exosomal markers and transmission electron microscopy. (C) Principal component analysis of exosomal miRs under four different conditions. (D–E) Heat map of differentially expressed miRs in both ESC-CM-Exo and iPSC-CM-Exo under hypoxic condition compared to control (normoxic condition). (F–G) Gene ontology analysis of abundant miRNAs in both ESC-CMs and iPSC-CMs.