Table 3.
Presumptive Etiology of SCA Among 133 SCA Cases With Autopsy or Clinical Workup Available
| All Cases (n=133) All Ages |
Ages 5–24 Years (n=49) | Ages 25–34 Years (n=84) | |||
|---|---|---|---|---|---|
| Sports-Related Activity (n = 14) |
Non-Sports- Related Activity (n = 35) |
Sports-Related Activity (n = 7) |
Non-Sports- Related Activity (n = 77) |
||
| Sudden arrhythmic death syndrome | 41 (31) | 5 (36) | 14 (40) | 1 (14) | 21 (27) |
| Coronary artery disease | 29 (22) | 1 (7) | 4 (14) | 2 (29) | 21 (27) |
| Hypertrophic cardiomyopathy | 19 (14) | 7 (50)* | 4 (11)* | 0 | 8 (10) |
| Isolated left ventricular hypertrophy | 9 (7) | 0 | 2 (6) | 0 | 7 (9) |
| Congenital heart disease | 5 (4) | 1 (7) | 1 (3) | 1 (14) | 2 (3) |
| Coronary anomaly | 4 (3) | 0 | 3 (9) | 0 | 1 (1) |
| Long QT syndrome | 3 (2) | 0 | 3 (9) | 0 | 0 |
| Acute myocarditis | 2 (2) | 0 | 1 (3) | 1 (14)† | 0 |
| Dilated cardiomyopathy‡ | 4 (3) | 0 | 0 | 0 | 4 (5) |
| Heart failure | 4 (3) | 0 | 0 | 0 | 4 (5) |
| Cardiomyopathy not otherwise specified | 2 (2) | 0 | 0 | 0 | 2 (3) |
| Restrictive cardiomyopathy | 1 (1) | 0 | 1 (3) | 0 | 0 |
| Mitral valve prolapse | 3 (2) | 0 | 0 | 0 | 3 (4) |
| Valvular heart disease | 3 (2) | 0 | 0 | 0 | 3 (4) |
| Idiopathic myocardial fibrosis | 3 (2) | 0 | 1 (3) | 1 (14) | 1 (1) |
| Right ventricular dysplasia | 1 (1) | 0 | 0 | 1 (14)† | 0 |
The table includes 133 subjects (108 with autopsy plus 25 without autopsy but with adequate clinical workup to determine cause of arrest). Five sports-related and 48 non-sports-related SCAs had insufficient information to assign a diagnosis. Values displayed are n (%). SCA indicates sudden cardiac arrest.
*
P=0.007.
†
P=0.08. All other P values >0.10. P values from Fisher exact test.
‡
One of the 4 patients with dilated cardiomyopathy had postpartum dilated cardiomyopathy with heart failure.