Table 4.
Presumptive Etiology of SCA Among 121 Cases, by Obesity
| Obese, BMI ≥30 kg/m2 (n=47) |
Nonobese, BMI <30 kg/m2 (n=74) |
P Value* | |
|---|---|---|---|
| Sudden arrhythmic death syndrome | 11 (23) | 30 (41) | 0.08 |
| Coronary artery disease | 16 (34) | 10 (14) | 0.01 |
| Hypertrophic cardiomyopathy | 5 (11) | 14 (19) | 0.31 |
| Isolated left ventricular hypertrophy | 8 (17) | 1 (1) | 0.002 |
| Congenital heart disease | 0 | 2 (3) | 0.52 |
| Coronary anomaly | 2 (4) | 2 (3) | 0.64 |
| Long QT syndrome | 2 (4) | 1 (1) | 0.56 |
| Acute myocarditis | 0 | 2 (3) | 0.52 |
| Dilated cardiomyopathy† | 1 (2) | 2 (3) | 1.0 |
| Heart failure | 1 (2) | 0 | 0.39 |
| Cardiomyopathy | 1 (2) | 0 | 0.39 |
| Restrictive cardiomyopathy | 0 | 1 (1) | 1.0 |
| Mitral valve prolapse | 0 | 3 (4) | 0.28 |
| Valvular heart disease | 0 | 2 (3) | 0.52 |
| Idiopathic myocardial fibrosis | 0 | 3 (4) | 0.28 |
| Right ventricular dysplasia | 0 | 1 (1) | 1.0 |
The table includes 121 of 133 subjects with autopsy or adequate clinical workup to determine cause of arrest who also had body mass index available. For patients aged 21 to 34 years, body mass index was the weight (kg) divided by height (m) squared, with obesity defined as body mass index ≥30 kg/m2. For patients aged 5 to 20 years, sex-specific body mass index-for-age charts were used21 to categorize underweight, normal weight, overweight, and obesity. Values are n (%).
*
P values from Fisher exact test.
†
One of the 4 patients with dilated cardiomyopathy had postpartum dilated cardiomyopathy with heart failure.