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. 2018 Apr 20;11(Suppl 2):31. doi: 10.1186/s12920-018-0346-x

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Kaplan-Meier plots for the top three markers in Table 3, and the corresponding KM plots for the individual genes in combination markers. In the combinations, all genes involved are assumed to have high expressions. For all figures, the red curves represent the survival probability of individuals with highly expressed genes/gene combinations, while the blue curves represent the survival probability of individuals with non-highly expressed genes/gene combinations. Indicated p-values are the adjusted log-rank p-values using the total correction factor k=920351. If the adjusted p-values exceed 1.0, p=1.0 is used. a The KM plot for the single gene GGCX, which is the top marker in Table 3 (most number of occurrences); b The KM plot for the single gene ANTXR2, the third marker with most number of occurrences; c The KM plot for the 2-gene combination MTF1,NBN (left-most), and the respective plots for the individual genes