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. Author manuscript; available in PMC: 2018 Apr 27.
Published in final edited form as: Nat Genet. 2018 Feb 26;50(3):381–389. doi: 10.1038/s41588-018-0059-2

Fig. 2. Partitioned heritability analysis of gene sets in schizophrenia.

Fig. 2

a, Heritability of genomic partitions and the six conditionally independent (‘significant’) gene sets (Table 2). The radius of each segment indicates the degree of enrichment, while the arc (angle of each slice) indicates the percentage of total SNP-based heritability explained. No relative enrichment (enrichment = 1) is shown by the dashed red line (and depletion equates to enrichment <1, inside red line). b, Heritability of the significant CNS gene sets dissected by their overlap with LoF-intolerant genes. Whiskers represent heritability or enrichment standard errors. Asterisks indicate the significance of each heritability enrichment (*P≤0.05, **P≤0.01, ***P≤0.001).