Table 1.
Demographics and aortic dimensions in controls and bicuspid aortic valve patients
| Healthy Controls | RL-BAV | RN-BAV | p-value | |
|---|---|---|---|---|
| N | 20 | 78 | 23 | |
| Age (years) | 50.04 ± 16.39 | 48.43 ± 13.15 | 46.97 ± 16.00 | 0.659 |
| Men (%) | 73.30 | 62.80 | 65.20 | 0.736 |
| Weight (kg) | 78.57 ± 9.24 | 76.17 ± 10.38 | 76.17 ± 10.38 | 0.270 |
| Height (cm) | 169.42 ± 7.73 | 170.00 ± 10.66 | 172.00 ± 9.91 | 0.433 |
| Body Surface Area (m2) | 1.89 ± 0.13 | 1.83 ± 0.21 | 1.88 ± 0.16 | 0.278 |
| Degree of Aortic Regurgitation (%) | 0.240 | |||
| 0 | – | 26.8 | 35.3 | |
| 1 | – | 21.1 | 5.9 | |
| 2 | – | 49.3 | 47.0 | |
| 3 | – | 2.8 | 11.8 | |
| Degree of Aortic Stenosis (%) | 0.695 | |||
| Absent | – | 92.9 | 90 | |
| Mild | – | 5.7 | 10 | |
| Moderate | – | 1.4 | 0 | |
| Maximum aortic velocity (m/s) | 97.34 ± 19.0 | 111.15 ± 24.35 | 119.32 ± 21.22 | 0.067 |
| Mean pressure gradient (mm Hg) | 3.24 ± 1.21 | 4.9 ± 1.13 | 5.69 ± 1.71 | 0.074 |
| Systolic Arterial Pressure (mm Hg) | 136.26 ± 19.47 | 134.18 ± 17.32 | 142 ± 17.76 | 0.064 |
| Diastolic Arterial Pressure (mm Hg) | 76.73 ± 8.85 | 75.72 ± 9.06 | 79.69 ± 9.11 | 0.133 |
| Sinus of Valsalva Diameter (mm) | 32.77 ± 3.44 | 36.68 ± 5.10 | 34.78 ± 2.69 | 0.796 |
| Ascending Aorta Diameter (mm) | 35.58 ± 2.96 | 39.86 ± 7 .51 | 40.30 ± 6.10 | 0.070 |
| z-score sinus of Valsalva diameter | 0.01 ± 0.84 | 1.41 ± 1.29 | 0.82 ± 1.11 | 0.001 |
| z-score ascending aorta diameter | 0.02 ± 0.71 | 2.87 ± 1.71 | 3.03 ± 1.4 | < 0.001 |
P-values reported are the result of ANOVA comparison between 3 groups: controls, RL-BAV and RN-BAV in continuous variables and Chi-square test for categorical variables