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. 2018 Apr 26;16:110. doi: 10.1186/s12967-018-1483-x

Fig. 1.

Fig. 1

Novel chimeric orthopoxvirus isolates CF33 and CF17 show superior cancer cell killing capability compared to the parental individual wild-type virus strains. Fifty-four solid cancer cell lines in the NCI-60 panel were infected with each virus at an MOI of 0.01. Cell viability was measured at 96 h post infection using MTS assays. Data represent the mean cell survival of 54 cancer cell lines ± sd. CF17 and CF33 demonstrated significantly better cell killing (p < 0.001) in the NCI-60 solid tumor cell lines than all nine parental orthopoxvirus strains