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. 2018 Apr 25;13(4):e0196419. doi: 10.1371/journal.pone.0196419

Table 2. Risk factors for the development of osteonecrosis of the jaw (ONJ) in patients receiving alendronate therapy.

Parameter Adjusted Odds Ratio 95% CI P*
Duration, ≥ 3 years vs. <3 years 3.00 1.33–6.76 0.008
Rheumatoid arthritis 4.94 1.64–14.90 0.005
Antecedent tooth extractions 9.60 4.33–21.29 0.000

* P-value was calculated from a multiple logistic regression analysis

Abbreviations: ONJ = osteonecrosis of the jaw; CI = confidence interval