. Author manuscript; available in PMC: 2018 Jun 27.

Published in final edited form as: ACS Nano. 2017 Jun 7;11(6):5680–5696. doi: 10.1021/acsnano.7b01110

Table 2. Pharmacokinetic Parameters Quantified from Intravascular Imaging Data Including Half-Life (T_1/2), Area under the Curve (AUC), and Clearance (Cl).

polymer	T_1/2 (min)	AUC (mg·min)/(L)	Cl (mL/min)
5k PEG	5.2 ± 1.7	127 ± 37	0.22 ± 0.07
20k PEG	22.4 ± 5.8	507 ± 152	0.06 ± 0.02
10k PMPC	8.4 ± 1.0	192 ± 23	0.13 ± 0.02
20k PMPC	26.3 ± 5.5	586 ± 157	0.05 ± 0.01
10k POEGMA	7.6 ± 0.4	165 ± 14	0.15 ± 0.01
20k POEGMA	7.4 ± 2.0	176 ± 45	0.15 ± 0.04
Cy5 nucleic acid	1.87 ± 0.20	75 ± 1.4	4.20 ± 0.27

Table 2. Pharmacokinetic Parameters Quantified from Intravascular Imaging Data Including Half-Life (T1/2), Area under the Curve (AUC), and Clearance (Cl).