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. 2018 Apr 26;13(4):e0196394. doi: 10.1371/journal.pone.0196394

Table 3. Microneutralization titers after heterosubtypic LPAIV inoculation against H3N8 antigen.

The table shows the proportion of positive samples and Log2 microneutralization (MN) titers (media and range) induced against H3N8 virus before and after inoculation of control or H3N8-primed mallards with increasing doses of H4N6 or H6N2 virus.

Challenge groups MN Antigen 0 DPI Median and range
Log2 titers
14 DPI Median and range
Log2 titers
H3N8XH4N6(101.8) H3N8 5/5 4.32 3/5 4.32 (0–5.32)
H4N6(101.8) 0/5 0 0/5 0
H3N8XH4N6(103) 4/5 4.32 (0–5.32) 3/5 4.32 (0–4.32)
H4N6(103) 0/5 0 0/5 0
H3N8XH4N6(104.1) 3/5 4.32 (0–5.32) 3/5 4.32 (0–6.32)
H4N6(104.1) 0/5 0 0/5 0
H3N8XH6N2(101.9) 2/5 0 (0–4.32) 3/5 4.32 (0–4.32)
H6N2(101.9) 0/5 0 0/5 0
H3N8XH6N2(103) 3/5 4.32 (0–7.32) 4/5 4.32 (0–5.32)
H6N2(103) 0/5 0 0/5 0
H3N8XH6N2(103.9) 4/5 4.32 (0–6.32) 3/5 6.32 (0–6.32)
H6N2(103.9) 0/5 0 0/5 0