Table 3. Microneutralization titers after heterosubtypic LPAIV inoculation against H3N8 antigen.
The table shows the proportion of positive samples and Log2 microneutralization (MN) titers (media and range) induced against H3N8 virus before and after inoculation of control or H3N8-primed mallards with increasing doses of H4N6 or H6N2 virus.
| Challenge groups | MN Antigen | 0 DPI | Median and range Log2 titers |
14 DPI | Median and range Log2 titers |
|---|---|---|---|---|---|
| H3N8XH4N6(101.8) | H3N8 | 5/5 | 4.32 | 3/5 | 4.32 (0–5.32) |
| H4N6(101.8) | 0/5 | 0 | 0/5 | 0 | |
| H3N8XH4N6(103) | 4/5 | 4.32 (0–5.32) | 3/5 | 4.32 (0–4.32) | |
| H4N6(103) | 0/5 | 0 | 0/5 | 0 | |
| H3N8XH4N6(104.1) | 3/5 | 4.32 (0–5.32) | 3/5 | 4.32 (0–6.32) | |
| H4N6(104.1) | 0/5 | 0 | 0/5 | 0 | |
| H3N8XH6N2(101.9) | 2/5 | 0 (0–4.32) | 3/5 | 4.32 (0–4.32) | |
| H6N2(101.9) | 0/5 | 0 | 0/5 | 0 | |
| H3N8XH6N2(103) | 3/5 | 4.32 (0–7.32) | 4/5 | 4.32 (0–5.32) | |
| H6N2(103) | 0/5 | 0 | 0/5 | 0 | |
| H3N8XH6N2(103.9) | 4/5 | 4.32 (0–6.32) | 3/5 | 6.32 (0–6.32) | |
| H6N2(103.9) | 0/5 | 0 | 0/5 | 0 |