Table 2. Differences between groups in the study outcomes.
| Outcomes | Differences between groups (95% confidence interval) | |||
|---|---|---|---|---|
| 24 weeks | p Value | 52 weeks | p Value | |
| GCF | ||||
| Intent-to-treat analysis | .11 (–.01 to .23) | .07† | .17 (.025 to .31) | .02‡ |
| Complete case analysis | .11 (–.01 to .24) | .08† | .17 (.03 to .32) | .02‡ |
| Concentration | ||||
| Intent-to-treat analysis | –.012 (–.24 to .21) | .9 | .17 (–.1 to .44) | .2 |
| Complete case analysis | .04 (–.2 to .28) | .75 | .23 (–.05 to .51) | .1 |
| Reasoning | ||||
| Intent-to-treat analysis | .04 (–.15 to .23) | .7 | .07 (–.15 to .28) | .5 |
| Complete case analysis | .01 (–.19 to .21) | .9 | .056 (–.16 to 27) | .6 |
| Planning | ||||
| Intent-to-treat analysis | .21 (–.06 to .48) | .1 | .16 (–.13 to .45) | .3 |
| Complete case analysis | .22 (–.08 to .52) | .15 | .16 (–.15 to .47) | .3 |
| Memory | ||||
| Intent-to-treat analysis | .17 (–.01 to .36) | .07† | .25 (.03 to .47) | .03‡ |
| Complete case analysis | .18 (–.02 to .38) | .08† | .25 (.02 to .48) | .03‡ |
NOTE. Data presented as z scores. Differences between groups calculated as M4 –M2. Calculated from linear mixed effects regression models that included group (M2 or M4), time (baseline, 24 and 52 weeks), and group × time interaction terms.
†Trends for differences between groups in estimated mean change from baseline
‡Significant differences between groups in estimated mean change from baseline.
Abbreviations: GCF, global cognitive functioning; M2, multiple-modality group; M4, multiple-modality, mind-motor group.