Fig 2. In vitro susceptibility to AmB of intracellular amastigotes of the sensitive control strains and less sensitive strains generated in vitro.

A) EC₅₀ values for AmB calculated for intracellular amastigotes of the less sensitive and sensitive strains. B) Percent reductions in the number of parasites of the sensitive control strains and less sensitive strains generated in vitro after exposure of infected macrophages to 0.5 μg/ml AmB. L. (V.) p. less s: L. (V.) panamensis less sensitive. L. (V.) b. s: L. (V.) braziliensis sensitive. L. (V.) b. less s: L. (V.) braziliensis less sensitive. L. (V.) g. s: L. (V.) guyanensis sensitive. L. (V.) g. less s: L. (V.) guyanensis less sensitive. The experiments were performed in triplicate.