Table 2. Tics rating parameters and related scores.

The rating parameters used are translated from the YGTSS used for patients, and include the number of body parts, frequency of the tic-like movement, complexity and impairment of the normal rats’ behavior.

Number of body parts 0–3 points	Frequency 0–4 points	Complexity 0–4 points	Impairment 0–2 points
• Limb (+1)	Calculated as average of: • Limb frequency/ intensity: 0 = none 1 = mild 2 = frequent 3 = continuous 4 = compulsive	0 = none 1 = mild 2 = moderate 3 = marked 4 = compulsive	0 = none 1 = mild 2 = strong
• Neck (+1)	• Neck frequency/ intensity: 0 = none 1 = mild 2 = frequent 3 = continuous 4 = compulsive
• Mouth (+1)	• Mouth frequency/ intensity: 0 = none 1 = mild 2 = frequent 3 = continuous 4 = compulsive