Table 2. Some candidate genes overlap with the potential regions of artificial selection in four domestic chicken populations.
| Chr. | Pos. (Mb)1 | P-value. (method)2 | Gene | Gene function |
|---|---|---|---|---|
| 1 | 55.42–55.43 | Fst0.039,iHS0.025;Fst0.005,CLR0.002; Fst0.008; Fst0.035; | PMCH | appetite, food intake[1] |
| 1 | 70.84–70.94 | Fst0.027,iHS0.027;Fst0.005;Fst0.005; Fst <0.001,Clr<0.001; | WNT7B | the developing central nervous system[38] |
| 1 | 71.72–71.74 | Fst0.025,iHS0.017;Fst0.002;Fst0.005,iHS0.035;Fst<0.001, Clr<0.001; | BCL2L14 | immune[47] |
| 1 | 72.42–72.44 | Fst0.025,iHS0.039;Fst<0.001;Fst0.005,iHS0.035;Fst<0.001, Clr<0.001; | KLHL42 | feed intake[42] |
| 1 | 72.51–72.53 | Fst0.025,iHS0.039;Fst<0.001;Fst0.005,iHS0.035;Fst<0.001, Clr<0.001; | PTHLH | bone development, eggshell[33] |
| 1 | 73.16–73.17 | Fst0.026,iHS0.018;Fst<0.001;Fst0.001;Fst<0.001,Clr<0.001; | FGF6 | growth[41] |
| 1 | 76.34–76.44 | Fst0.025,iHS0.004;Fst0.001,iHS0.006; Fst0.031,iHS0.004,CLR0.01; Fst<0.001,Clr<0.001; | OVST | eggshell[35] |
| 1 | 76.90–76.92 | Fst0.025,iHS0.003;Fst0.007,iHS0.008;Fst0.031,iHS0.004,CLR0.01;Fst0.013,CLR<0.001; | SCNN1A | cation transportation, eggshell[34] |
| 1 | 77.35–77.38 | Fst0.025,iHS0.003;iHS0.008;Fst0.015,iHS0.004;Fst<0.001,CLR<0.001; | LPCAT3 | feed intake[46] |
| 2 | 14.04–14.88 | Fst0.042,iHS0.036;Fst0.036,CLR0.004;Fst0.007,iHS0.005,CLR0.014; Fst0.037,iHS 0.041,CLR0.014; | ITGB1 | skeletal myogenesis[48] |
| 3 | 19.37–19.43 | Fst0.038,iHS0.048; Fst0.031; Fst0.004;Fst 0.006, Clr 0.006; | TGFB2 | growth traits[44] |
| 3 | 105.92–106.1 | Fst 0.019,iHS0.013; Fst 0.022; Fst 0.001; Fst 0.049; | NCOA1 | total egg production[43] |
| 5 | 13.77–13.78 | Fst0.009,iHS0.026;Fst0.031;Fst0.001,CLR0.017;Fst0.004,iHS0.008; | IGF2 | growth and carcass traits[45] |
| 5 | 40.81–40.86 | Fst0.005,iHS0.004,CLR0.016;Fst<0.001;Fst<0.001,CLR0.007; Fst <0.001, CLR 0.004; | TSHR | the reproductive machinery[1, 4] |
| 5 | 49.02–49.03 | Fst0.006,iHS0.031;Fst0.005;Fst0.036,iHS0.047;Fst<0.001,CLR<0.001; | DLK1 | muscle hypertrophy[4] |
| 6 | 14.82–14.84 | Fst0.032,iHS0.003;Fst0.001;Fst0.036,iHS0.023,CLR0.008;Fst0.013,iHS0.021,CLR0.008; | COMTD1 | Pigmentation[49] |
| 7 | 22.54–22.55 | Fst0.038,iHS0.018;Fst0.022,CLR0.004;Fst0.004,iHS0.014;Fst0.033; | PRKAG3 | Meat quality[3] |
| 11 | 16.18–16.63 | Fst0.037,iHS0.012;Fst0.005;Fst0.021;Fst<0.001,CLR0.007; | CDH13 | Disease-resistant[50] |
| 18 | 4.47–4.51 | Fst0.006;Fst0.007;Fst0.004,CLR0.007;Fst0.004,CLR0.015; | PRPSAP1 | Abdominal fatness deposition[51] |
1 This column presents the position of candidate genes which overlap with or close to the potential regions of artificial selection.
2 This column presents the genome-wide P-values of three statistics, corresponding to AR_VO, PB, RH_WL and JH_JF with semicolons.