Table 1. Number of articles including quality assessment items.

Quality assessment item	Randomization of allocation	Blinded or automated assessment	Sample size calculation	Exact sample size description	Statement of compliance with regulatory requirements	Statement on conflict of interest	Statement of compliance with ARRIVE
Number of articles (%)	18/77 (23.4%)	92/122 (75.4%)	1/122 (0.8%)	98/122 (80.3%)	118/122 (96.7%)	66/122 (54.1%)	0/122 (0%)

Percentages were calculated using all 122 articles, except in the case of randomization, which was calculated based on 77 articles, as it is not applicable to genetic interventions. In the case of blinding, 68 articles used automated analysis and 24 used blinded observers, totaling 92 articles scored for this item.