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. 2018 Apr 16;14(4):e1006103. doi: 10.1371/journal.pcbi.1006103

Fig 2. RNA-induced displacement of Lβ3β4 and α2.

Fig 2

(A) Depiction of the “open” and “closed” structural states of Lβ3β4 for exemplar structures of ATP (blue) and ssRNA+ATP (green) simulations. (B) Hydrophobic interactions between Lβ3β4 and α2 stabilize the “open” conformation. Furthermore, Val227 and Met231 (α2) are pushed in towards the NTPase active site when Lβ3β4 is in the “open” conformation. (C) RMSD of α2 (residues 224 to 235) backbone atoms referenced against the ssRNA+ATP crystal structure (PDB ID: 2JLV).