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. 2018 Apr 16;14(4):e1006103. doi: 10.1371/journal.pcbi.1006103

Fig 8. Correlated motions of protein motifs observed to experience RNA- or NTPase substrate-induced allostery.

Fig 8

(A) The average COM-COM residue pair correlation heat map for the ssRNA+ATP system abridged with a distance cutoff of 15 Å. Lines drawn highlight the structural motifs discussed in the previous two sections (α2, motifs II and IVa). Panels (B) and (C) are magnifications of off-diagonal regions in (A) that correspond to the correlations between α2 and motif II or motif IVa, respectively. Hotspots within these regions identify the short-range residue-residue interactions that couple the structures. Panels (D) and (E) provide structural depiction of these residue-residue interactions.