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. 2018 Apr 16;12(4):e0006438. doi: 10.1371/journal.pntd.0006438

Fig 7. Ivermectin inhibits EV release from filarial nematodes.

Fig 7

(A) 1 μM IVM reduces EV release by B. malayi in vitro. Microfilaria (mf), L3, adult male (AM) and female (AF) were incubated in RPMI containing IVM or vehicle control. Media was collected after 24 hr and EV isolated and quantified. N = 3 (minimum), mean ± SEM, *P<0.05, **P<0.01, ****P<0.0001. (B) 1 μM IVM reduces EV release in vitro by IVM susceptible Missouri strain (MO) D. immitis L3 but not IVM reduced susceptibility JYD-34 strain. N = 3 (minimum), mean ± SEM, **P<0.01, ns not significant.