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. 2018 Apr 4;52(6):1886–1898. doi: 10.3892/ijo.2018.4356

Figure 4.

Figure 4

Silencing LTBP2 decreases the proliferative ability of GC cells. The knockdown efficiency of LTBP2 in (A) SGC7901 and (B) BGC823 cells was investigated using western blotting and reverse transcription-quantitative chain reaction analyses. *P<0.05 and **P<0.01 vs. WT (C) Representative images of the colony-formation assay and quantification of the results indicating decreased colony-formation ability of GC cells with knockdown of LTBP2. *P<0.05 vs. Mock (D) CCK-8 assays indicating impaired proliferative ability of GC cells with knockdown of LTBP2. LTBP2, latent transforming growth factor-β-binding protein 2; GC, gastric cancer; WT, wild-type; Mock, cells infected with mock lentivirus; OD, optical density; sh, short hairpin.