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. 2017 Dec 5;8(2):401–409. doi: 10.1534/g3.117.300292

Table 1. χ2 analysis of cleft palate and exencephaly indicates that both phenotypes are contingent with the fosse mutant phenotype.

Phenotype fosse Observed Wild-Type Expected Wild-Type Observed
Unaffected 51 (82.3%) 128 155
Cleft Palate 11 (17.7%) 27 0a
aP < 0.0001
Unaffected 46 (74.2%) 115 155
Exencephaly 16 (25.8%) 40 0a
aP = 0.0009
Total Embryos 62 155
a

P-values indicate that the lack of cleft palate and exencephaly in unaffected littermates is a significant deviation from ratio observed among the fosse cohort (percentages in parentheses).