Table 2 .
G0 and G1 mutagenesis rates in three different Anopheles species.
| sgRNA | # Inj. | Survivors | Mosaic (%) | G0 M × White F | White M × G0 F | G0 M × G0 F | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M | F | Total (%) | M (%) | F (%) | G1 Mutant M (%) | G1 Mutant F (%) | G1 Mutant M (%) | G1 Mutant F (%) | G1 Mutant M (%) | G1 Mutant F (%) | |||
| Anopheles coluzzii | AcsgRNA1 | 612 | 76 | 62 | 138 (23) | 71 (93) | 54 (87) | 991 (93) | 117 (91) | 851 (91) | 1232 (94) | 881 (86) | 939 (81) |
| AcsgRNA2 | 447 | 53 | 36 | 89 (20) | 17 (32) | 9 (25) | 1038 (88) | 1273 (84) | 751 (89) | 882 (91) | 751 (45) | 846 (49) | |
| Anopheles albimanus | AasgRNA1 | 573 | 81 | 58 | 139 (24) | 74 (91) | 43 (74) | N/A | N/A | 1317 (60) | 1577 (62) | ||
| AasgRNA2 | 511 | 79 | 68 | 147 (29) | 0 | 0 | N/A | N/A | N/A | N/A | |||
| Anopheles funestus | AfsgRNA1 | 237 | 15 | 11 | 26 (11) | 8 (53) | 7 (64) | N/A | N/A | 53 (65) | 92 (71) | ||
| AfsgRNA2 | 352 | 21 | 16 | 37 (11) | 5 (24) | 4 (25) | N/A | N/A | 37 (51) | 62 (61) | |||