Table 2. Nucleotide diversity in various rodent colonies.
Species | π | Number of Individuals | Breeding Scheme | Region of Genome for Which π Was Evaluated | Approximate Number of Bases Surveyed | Citation |
---|---|---|---|---|---|---|
M. unguiculatus | 0.0059 | 24 | Outbred colony | Near autosomal restriction sites (GBS) | 2,200,000 | This article |
M. musculus subsp.a | 0.0289 | 69 | Collaborative Cross | Whole genome sequencing | 2,300,000,000 | Srivastava et al. (2017) |
M. musculus subsp. | 0.0055 | 8 | Eight inbred strains | Autosomal genes (Sanger) | 14,000 | Salcedo et al. (2007) |
M. musculus domesticus | 0.0102 | 64 | Wild caught | Autosomal genes (Sanger) | 15,000 | Salcedo et al. (2007) |
M. musculus musculus | 0.0054 | 26 | Wild caught | Autosomal genes (Sanger) | 15,000 | Salcedo et al. (2007) |
Peromyscus maniculatusb | 0.0006 | 13 | Outbred colony | Near restriction sites (ddRAD) | 400,000 | Weber et al. (2013) |
P. polionotusb | 0.0010 | 1 | Outbred colony | Near restriction sites (ddRAD) | 400,000 | Weber et al. (2013) |
Phodopus campbellic | 0.0006 | 14 | Outbred colony | Near restriction sites (ddRAD) | 1,300,000 | J. Good, personal communication |
P. sungorusc | 0.0002 | 11 | Outbred colony | Near restriction sites (ddRAD) | 1,400,000 | J. Good, personal communication |
R. norvegicus | 0.0015–0.0029 | 96 | 96 inbred strains | CEL I-based SNP detection | 5,800,000 | Smits et al. (2004) |
R. norvegicus | 0.0022 | 58 | Wild caught | Autosomal genes (Sanger) | 10,000 | Ness et al. (2012) |
Based on mean value of 69 Collaborative Cross individuals. Data from the column titled “% het (autosomes) in sequenced sample” in table S2 of Srivastava et al. (2017). Approximate number of bases surveyed is based on a genome size of 2.7 GB divided by the mean “% coverage at 15×.”
The Peromyscus animals evaluated here are the BW and PO strains originating with the Peromyscus stock center, bred at Harvard University in the Hoekstra laboratory, and sequenced by Weber et al. (2013).
The Phodopus animals evaluated here are from the Good laboratory at the University of Montana described in Brekke and Good (2014).