Table 1. General Risk Reduction Strategies.

The slow evolution of breast cancer allows for multiple types of lifestyle interventions to reduce risk [6, 33].

HRT: hormone replacement therapy

Types of Intervention	Mechanism of Action	Specific Approach	Relative Risk Reduction
Childbearing patterns (first live birth under 18 vs. over 30 or null parity)	Early pregnancy leads to earlier terminal differentiation of ductal epithelium	Pregnancy; prenatal education	40%
Breastfeeding	Causes maturation of ductal epithelium	Nursing education; providing spaces for nursing mothers at work and/or in public	4% reduction for every year of breastfeeding
Avoidance of hormone supplements (HRT)	Unknown; HRT use is associated with breast cancer	Physician education	26%
Post-menopausal weight management	Reduction in adipose tissue that stores hormones	Community and physician education; improved access to fitness facilities, training, and/or equipment	20-30%
Healthy dietary habits and physical activity	Lowers body fat, enhances immune function, affects hormone levels, and delays menarche in children	Community education and legislation for mandated food labeling; Exercise education and planned/mandatory exercise programs	20-30%