Table III.
Alterations of cytokine levels in stored erythrocyte suspensions.
| (pg/mL) | IL-8 | IL-13 | |||
|---|---|---|---|---|---|
|
|
|
||||
| LR-ES | NL-ES | LR-ES | NL-ES | ||
| DAY 0 | median | 25.46 | 40.01 | 11.36 | 13.19 |
| (min:max) | (17.65:112.60) | (25.46:200.39) | (8.48:173.26) | (4.44:174.64) | |
|
| |||||
| DAY 21 | median | 34.56 | 63.50 | 16.05 | 16.38 |
| (min:max) | (12.45:102.84) | (27.41:1218.76) | (4.44:639.15) | (0.74:61.62) | |
|
| |||||
| DAY 42 | median | 28.71 | 36.51 | 23.28 | 21.43 |
| (min:max) | (20.26:495.62) | (27.41:2214.37) | (5.11:877.63) | (0.00:142.68) | |
|
| |||||
| IL-17A | IL-22 | ||||
|
|
|||||
| LR-ES | NL-ES | LR-ES | NL-ES | ||
|
| |||||
| DAY 0 | median | 5.58 | 4.24 | 0.00 | 3.67 |
| (min:max) | (2.55:9.78) | (2.93:14.41) | (0.00:0.00) | (0.00:650.46) | |
|
| |||||
| DAY 21 | median | 6.79 | 5.78 | 0.00 | 0.00 |
| (min:max) | (5.25:10.74) | (2.07:12.96) | (0.00:0.00) | (0.00:2.33) | |
|
| |||||
| DAY 42 | median | 9.20 | 3.66 | 0.00 | 0.00 |
| (min:max) | (6.30:13.93) | (1.87:14.70) | (0.00:0.00) | (0.00:454.40) | |
|
| |||||
| IFN-γ | TGF-β | ||||
|
|
|||||
| LR-ES | NL-ES | LR-ES | NL-ES | ||
|
| |||||
| DAY 0 | median | 22.88 | 23.34 | 0.00 | 1.39 |
| (min:max) | (0.01:161.48) | (0.01:481.48) | (0.00:0.00) | (0.00:62.72) | |
|
| |||||
| DAY 21 | median | 26.60 | 13.81 | 0.00 | 55.87 |
| (min:max) | (0.00:365.67) | (0.55:380.09) | (0.00:0.00) | (0.00:106.06) | |
|
| |||||
| DAY 42 | median | 12.65 | 19.39 | 0.00 | 36.84 |
| (min:max) | (0.00:304.74) | (1.48:537.30) | (0.00:0.00) | (0.00:162.61) | |
Results (pg/mL) are presented as the median (minimum and maximum) values. p-values <0.05 are considered as statistically significant and significant changes are shown in italic. LR-ES: leucoreduced erythrocyte suspension; NL-ES: non-leucoreduced erythrocyte suspension; IL-8: interleukin-8; IL-13: interleukin-13; IL-17A: interleukin-17A; IL-22: interleukin-22; IFN-γ: interferon-gamma; TGF-β; transforming growth factor-beta.