Table 1.

Univariate analysis and Multivariate analysis of the risk score.

Variables, n (%)	patient (n = 537)	Univariate analysis HR (95%CI)	P a	Multivariate analysis HR (95%CI)	P b
Gender
Female	191(35.6)	ref		ref
Male	346(64.4)	0.949(0.692, 1.302)	0.746	0.893(0.638, 1.251)	0.512
Age
≤60	266(49.5)	ref		ref
>60	271(50.5)	1.812(1.322, 2.483)	<0.001	1.603(1.157, 2.22)	0.005
Grade
G1 + G2	244(45.4)	ref		ref
G3 + G4	285(53.1)	2.824(1.977, 4.033)	<0.001	1.618(1.092, 2.395)	0.016
Laterality
left	253(47.1)	ref		ref
right	283(52.7)	0.682(0.501, 0.927)	0.015	0.843(0.607, 1.17)	0.307
Pathologic stage
I + II	326(60.7)	ref		ref
III + IV	208(38.7)	4.196(3.014, 5.843)	<0.001	1.678(0.786, 3.579)	0.181
T stage
T1 + T2	344(64.1)	ref		ref
T3 + T4	193(35.9)	3.533(2.577, 4.843)	<0.001	1.166(0.605, 2.248)	0.647
M stage
M0	426(79.3)	ref		ref
M1	79(14.7)	4.482(3.265, 6.153)	<0.001	2.395(1.599, 3.587)	<0.001
MX	30(5.6)	0.352(0.049, 2.526)	0.299	0.415(0.058, 2.988)	0.382
N stage
N0	240(44.7)	ref		ref
N1	17(3.2)	3.286(1.747, 6.182)	<0.001	1.239(0.604, 2.542)	0.559
NX	280(52.1)	0.746(0.543, 1.024)	0.070	0.746(0.532, 1.044)	0.088
Race
white	466(86.8)	ref		—	—
others	64(11.9)	0.675(0.344, 1.325)	0.253	—	—
Risk score
Low risk	370(68.9)	ref		ref
High risk	156(29.1)	2.711(1.987, 3.697)	<0.001	1.606(1.139, 2.265)	0.007

^aUnivariate Cox regression; ^bMultivariate Cox regression.