Table 3.
FXII activity, antigen, and ratio in multiple sclerosis patients over four time points.
| Time points | |||||
|---|---|---|---|---|---|
| N 49 | T0 | T1 | T2 | T3 | p-value |
| FXII:c % | 0.031 | ||||
| Mean | 114.5 | 110.4 | 114.1 | 110.0 | |
| Lower 95% CI | 108.6 | 104.5 | 107.3 | 103.8 | |
| Upper 95% CI | 120.4 | 116.3 | 120.8 | 116.2 | |
| FXII:Ag % | 0.596 | ||||
| Mean | 105.1 | 107.8 | 108.8 | 105.8 | |
| Lower 95% CI | 95.87 | 98.06 | 99.54 | 96.87 | |
| Upper 95% CI | 114.4 | 117.5 | 118.0 | 114.8 | |
| FXII:ratio | 0.151 | ||||
| Mean | 1.16 | 1.10 | 1.10 | 1.09 | |
| Lower 95% CI | 1.07 | 1.01 | 1.03 | 1.02 | |
| Upper 95% CI | 1.25 | 1.18 | 1.17 | 1.16 | |
FXII:c, factor XII activity; FXII:Ag, factor XII antigen; FXII:ratio, FXII:c/FXII:Ag; CI, confidence interval; N, number.
ANOVA for repeated measures was used to test FXII:c, FXII:Ag, and FXII:ratio across the four time points.