Table 1.
Treatment | Infection indexa |
Intracellular proliferationb |
||
---|---|---|---|---|
Mean ±SD | % Inhibition vs. control | Mean ±SD | % Inhibition vs. control | |
Controlc | 175 ± 3 | - | 3368 ± 1123 | - |
KP 25 μg/mL | 118 ± 22*** | 33 | 1557 ± 225** | 54 |
KP 50 μg/mL | 106 ± 16*** | 39 | 858 ± 130*** | 75 |
KP 100 μg mL | 42 ± 5*** | 76 | 253 ± 100*** | 92 |
KP 200 μg/mL | 22 ± 17*** | 87 | 181 ± 45*** | 95 |
SP 200 μg/mL | 158 ± 7 | 9 | 2315 ± 779 | 31 |
aInfection index: number of infected cells per 200 examined cells; bintracellular proliferation: number of parasites per 200 examined cells; cmedium alone. SP: scrambled synthetic peptide containing the same amino acids of KP in a different order. ∗∗P < 0.01, ∗∗∗P < 0.001, as determined by one-way ANOVA with Dunnett post hoc test vs. control.