Table 4. Correlation of AQPs genes expression level with OS in ovarian cancer patients with different chemotherapeutic agents.
| AQPs | Chemotherapy | Cases | HR (95% CI) | P-value |
|---|---|---|---|---|
| AQP0 | Contains Platin | 1409 | 1.16 (1.01–1.34) | 0.033* |
| Contains Taxol | 793 | 1.24 (1.03–1.5) | 0.025* | |
| Contains Taxol + Platin | 776 | 1.28 (1.06–1.55) | 0.012* | |
| AQP1 | Contains Platin | 1409 | 1.28 (1.09–1.49) | 0.0022* |
| Contains Taxol | 793 | 1.25 (1.03–1.52) | 0.026* | |
| Contains Taxol + Platin | 776 | 1.26 (1.03–1.54) | 0.021* | |
| AQP3 | Contains Platin | 1409 | 0.82 (0.7–0.96) | 0.014* |
| Contains Taxol | 793 | 0.76 (0.61–0.95) | 0.016* | |
| Contains Taxol + Platin | 776 | 0.77 (0.62–0.96) | 0.018* | |
| AQP4 | Contains Platin | 478 | 1.52 (1.13–2.03) | 0.005* |
| Contains Taxol | 357 | 1.31 (0.98–1.74) | 0.064 | |
| Contains Taxol + Platin | 356 | 1.32 (0.99–1.75) | 0.06 | |
| AQP5 | Contains Platin | 1409 | 0.85 (0.73–0.99) | 0.033* |
| Contains Taxol | 793 | 1.15 (0.95–1.39) | 0.14 | |
| Contains Taxol + Platin | 776 | 1.17 (0.96–1.41) | 0.12 | |
| AQP6/AQP2L | Contains Platin | 1409 | 0.8 (0.7–0.93) | 0.0023* |
| Contains Taxol | 793 | 0.79 (0.65–0.95) | 0.013* | |
| Contains Taxol + Platin | 776 | 0.77 (0.63–0.94) | 0.012* | |
| AQP8 | Contains Platin | 1409 | 0.86 (0.74–0.99) | 0.038* |
| Contains Taxol | 793 | 0.84 (0.69–1.03) | 0.096 | |
| Contains Taxol + Platin | 776 | 0.83 (0.68–1.02) | 0.07 | |
| AQP10 | Contains Platin | 478 | 0.74 (0.57–0.97) | 0.027* |
| Contains Taxol | 357 | 1.32 (0.92–1.89) | 0.14 | |
| Contains Taxol + Platin | 356 | 1.3 (0.91–1.86) | 0.15 | |
| AQP11 | Contains Platin | 478 | 0.74 (0.58–0.95) | 0.017* |
| Contains Taxol | 357 | 0.65 (0.48–0.89) | 0.0067* | |
| Contains Taxol + Platin | 356 | 0.65 (0.47–0.88) | 0.0057* |
*
P<0.05.