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. 2018 Apr 27;38(2):BSR20171350. doi: 10.1042/BSR20171350

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© 2018 The Author(s).

This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).

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(A) Using STRING, the network of mRNA was constructed with 48 DE-mRNAs, and a significant interaction between these genes was found. Green nodes represent up-regulated genes, pink nodes represent down-regulated genes. The size of the node represents the number of genes that interact with it, the larger the node, the more genes that interact with it. Amongst the red circles is a member of the cathepsins family such as CTSB. (B) Four DE-lncRNAs were used to construct a network between lncRNA and mRNA. The nodes of the triangle represent lncRNA, and the circular nodes represent mRNA. Green nodes represent up-regulated genes, pink nodes represent down-regulated genes.