Table 1. Patient characteristics (n=42).
Variables | AR | p | ||||
---|---|---|---|---|---|---|
Negative | Positive | |||||
Age (yr) | 47 (33–69) | 49 (33–69) | 45 (39–61) | 0.390 | ||
Parity | 0.323 | |||||
0 | 3 (7.1) | 2 (6.5) | 1 (9.1) | |||
1 | 6 (14.3) | 3 (9.7) | 3 (27.3) | |||
≥2 | 33 (78.6) | 26 (83.9) | 7 (63.6) | |||
BMI (kg/m2) | 23.06 (18.04–32.79) | 23.50 (18.65–32.79) | 22.55 (18.04–26.18) | 0.112 | ||
Menopause | 0.273 | |||||
Yes | 27 (64.3) | 18 (41.9) | 9 (81.8) | |||
No | 15 (35.7) | 13 (58.1) | 2 (18.2) | |||
Size of tumor (cm) | 7.8 (2.5–21.0) | 8.8 (2.5–21.0) | 6.5 (3.5–14.0) | 0.439 | ||
<10 | 27 (64.3) | 19 (61.3) | 8 (72.7) | 0.717 | ||
≥10 | 15 (35.7) | 12 (38.7) | 3 (27.3) | - | ||
FIGO stage | 0.311 | |||||
I | 26 (61.9) | 18 (58.1) | 8 (72.7) | |||
II | 4 (9.5) | 2 (6.5) | 2 (18.2) | |||
III | 3 (7.1) | 3 (9.7) | 0 (0) | |||
IV | 9 (21.4) | 8 (25.8) | 1 (9.1) | |||
Mitotic count (mitoses/10 high-power fields) | 1.000 | |||||
≤10 | 13 (31.0) | 9 (37.5) | 4 (40.0) | |||
>10 | 21 (50.0) | 15 (62.5) | 6 (60.0) | |||
Unknown | 8 (19.0) | - | - | |||
Histologic subtype | 0.642 | |||||
Spindle cell | 30 (71.4) | 23 (74.2) | 7 (71.4) | |||
Epithelioid | 7 (16.7) | 5 (16.1) | 2 (18.2) | |||
Myxoid | 4 (9.5) | 2 (6.5) | 2 (18.2) | |||
Other | 1 (2.4) | 1 (3.2) | 0 (0) | |||
Recurrence | 23 (54.8) | 20 (64.5) | 3 (27.3) | 0.043 | ||
Pattern of recurrence | 0.791 | |||||
Loco-regional | 9 (39.1) | 8 (40.0) | 1 (33.3) | |||
Distant | 12 (52.2) | 10 (50.0) | 2 (66.7) | |||
Both | 2 (9.7) | 2 (10.0) | 0 (0) | |||
Death | 14 (33.3) | 14 (45.2) | 0 (0) | 0.007 | ||
Hysterectomy | 0.481 | |||||
With unilateral ovarian preservation | 15 (35.7) | 10 (32.3) | 5 (45.5) | |||
With BSO | 27 (64.3) | 21 (67.7) | 6 (54.5) | |||
Lymph node dissection | 19 (45.2) | 14 (45.2) | 5 (45.5) | 1.000 | ||
LNM | 1.000 | |||||
Positive | 1 (5.3) | 1 (7.1) | 0 (0) | |||
Negative | 18 (94.7) | 13 (92.9) | 5 (100.0) | |||
Adjuvant treatment | 0.761 | |||||
None | 15 (35.7) | 10 (32.3) | 5 (45.5) | |||
Chemotherapy | 25 (59.5) | 19 (61.3) | 6 (54.5) | |||
Radiotherapy | 1 (2.4) | 1 (3.2) | 0 (0) | |||
Both (chemotherapy+radiotherapy) | 1 (2.4) | 1 (3.2) | 0 (0) |
Values are presented as median (range) or number (range or %).
AR, androgen receptor; BMI, body mass index; BSO, bilateral salpingo-oophorectomy; FIGO, international federation of gynecology and obstetrics; LNM, lymph node metastasis.