Table 2. Clinicopathological characteristics, treatment, and outcomes of patients with recurrence of uterine serous carcinoma.
Case | Age | Stage | Depth of invasion | Cervical stromal involvement | LVSI | Pelvic cytology | Tumor size (mm) | Site of recurrence | Treatment for recurrence | DFS (mo) | Status at last follow-up |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 62 | IA | <50% | Present | Present | Positive | 38 | Peritoneum+PLN | Chemotherapy | 11 | DOD |
2 | 61 | II | <50% | Absent | Absent | Positive | 55 | Peritoneum | Chemotherapy | 15 | DOD |
3 | 65 | II | ≥50% | Absent | Absent | Negative | 25 | Peritoneum | Chemotherapy | 19 | DOD |
4 | 72 | II | ≥50% | Absent | Absent | Positive | 33 | Peritoneum | Chemotherapy | 5 | DOD |
5 | 72 | IA | Endometrium | Present | Absent | Positive | 25 | Peritoneum | Chemotherapy | 10 | LOF |
6 | 76 | IA | Endometrium | Present | Absent | Negative | 25 | Lung+pericardium+cervical lymph node | Chemotherapy | 36 | DOD |
7 | 58 | IA | <50% | Present | Absent | Positive | 37 | Lung, abdominal mass | Chemotherapy | 5 | DOD |
8 | 77 | II | ≥50% | Absent | Present | Negative | 42 | Lung | Chemotherapy | 22 | DOD |
9 | 66 | II | <50% | Absent | Absent | Negative | 25 | Brain+lung | RT | 67 | DOD |
10 | 64 | IA | <50% | Present | Absent | Negative | 29 | Vagina (12 mo), lung (27 mo) | IVRT+surgery | 12 | NED |
11 | 78 | II | ≥50% | Absent | Present | Negative | 90 | Vagina | IVRT | 4 | DOD |
12 | 77 | II | ≥50% | Absent | Present | Negative | 60 | Vagina | IVRT | 7 | DOD |
13 | 73 | IA | Endometrium | Present | Absent | Positive | 20 | Liver+pelvic mass | Chemotherapy | 41 | DOD |
14 | 58 | IB | ≥50% | Present | Present | Positive | 40 | Pleura | Chemotherapy | 26 | DOD |
15 | 63 | IA | <50% | Present | Present | Positive | 15 | Mesentery | Surgery+RT | 21 | NED |
16 | 61 | IB | ≥50% | Present | Present | Negative | 35 | PAN+Virchow's node+subcutaneous tumor | Chemotherapy+RT | 17 | DOD |
17 | 62 | IA | <50% | Present | Absent | Negative | 25 | PAN | Surgery+RT | 10 | NED |
18 | 67 | II | <50% | Absent | Absent | Negative | 100 | PAN | Chemotherapy | 8 | NED |
DFS, disease-free survival; DOD, death on disease; IVRT, intravaginal radiotherapy; LOF, loss of follow-up; LVSI, lymphovascular space invasion; NED, no evidence of disease; PAN, para-aortic lymph node; PLN, pelvic lymph node; RT, radiation therapy.