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. 2018 Mar 19;15(5):4229–4242. doi: 10.3892/etm.2018.5966

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Analysis of C-MET expression by immunohistochemistry in colorectal carcinomas. C-MET expression was localized in the membrane and its expression was observed predominantly in cancer cells. (A) Negative C-MET staining in a cancerous tissue sample (magnification, ×100). (B) Positive C-MET staining in tumor cells (upper), with negative or weak staining in adjacent epithelial cells (lower) (magnification, ×100). (C) Strong C-MET staining in tumor nests (magnification, ×100). (D) Positive membrane staining, as observed in the majority of tumor cells (magnification, ×200). C-MET, c-mesenchymal epithelial transition factor.