Average survival of exponentially growing
Escherichia coli cells after 3 h of ciprofloxacin (CIP) treatment.
EC93 cells with or without cdiBAI loci (n = 5).
Uropathogenic E. coli 536 (UPEC 536) cells with or without CdiA C‐terminal toxin and immunity (cdiA
ΔCT‐I) (n = 7).
MG1655 cells with empty, cdiBA‐CT‐I
EC93, cdiBA‐CT‐I
UPEC536 or cdiBA‐CT‐I
EC869 plasmids (n = 5, 4, 4, 3).
MG1655 cells with chromosomally encoded cdiBA, cdiBA‐CT‐I
EC93 or cdiBA‐CT‐I
UPEC536 (n = 7, 4, 3).
MG1655 bamA
Sty cells with empty, cdiBA‐CT‐I
EC93
, cdiBA‐CT‐I
UPEC536 or cdiBA‐CT‐I
EC869 plasmids (n = 8, 3, 3, 5).
Data information: Scales are logarithmic for (A, C–E) and linear for (B). Error bars represent s.e.m., and
n‐values indicate biological replicates. Statistical significance was determined using Mann–Whitney
U‐test. *
P < 0.05.
Source data are available online for this figure.