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Silencing RON decreased Akt and MAPK phosphorylation in the 5637 cells. Western blot analysis measured the effects of RON knockdown on the phosphorylation levels of Akt, ERK1/2 and p38. Akt, protein kinase B; MAPK, mitogen-activated protein kinase; RON, macrophage stimulating 1 receptor; ERK1/2, extracellular signal-regulated kinase 1/2.
